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Tempus wins USD 9.5m in ARPA-H funding to develop autonomous cardiology AI

Tempus wins USD 9.5m in ARPA-H funding to develop autonomous cardiology AI

Tempus AI (Nasdaq: TEM) secured up to USD 9.5 million from the Advanced Research Projects Agency for Health (ARPA-H) to develop and clinically validate an autonomous AI system for heart failure care under the agency's ADVOCATE program.

The award will support development of the agent and a multi-center prospective study intended to assess its use in clinical workflows. Tempus said the system will integrate electronic health record data with information from home-based monitoring devices and support functions including symptom monitoring, medication coordination, virtual rehabilitation, and scheduling.

The platform will build on several existing Tempus products, including Olivia, its patient-facing health concierge; Tempus Next, a care-gap identification platform that the company said has screened more than 2.7 million cardiology patients; and three FDA-cleared ECG-based AI products.

Tempus received US FDA clearance for an ECG-based AI product in August 2026 designed to identify patients showing signs associated with pulmonary hypertension, marking its third cleared ECG-AI product in cardiovascular care.

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The ARPA-H funding was awarded through ADVOCATE, or Agentic AI-Enabled CardioVascular Care Transformation, a federal initiative focused on developing and validating autonomous clinical AI systems for cardiovascular care. The program is intended to support technologies capable of carrying out selected care-management functions with limited direct clinician oversight.

Tempus said its project will focus initially on heart failure, a condition affecting more than 6 million people in the US. The company cited gaps in access to specialist care and low uptake of guideline-recommended therapies as areas the system is intended to address.

The prospective study will provide the first major test of whether Tempus can combine its existing cardiology AI tools into a clinically validated autonomous care platform and could generate evidence relevant to a future regulatory submission.


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