AllSci News

Systematic, data-driven science coverage · Tuesday, October 6, 2026
The AllSci BriefFree, systematic R&D and deal news. Daily.
Editor’s Picks
Vial starts Phase Ib asthma trial of IL-13 x TSLP bispecific targeting twice-yearly dosing
Development

Vial starts Phase Ib asthma trial of IL-13 x TSLP bispecific targeting twice-yearly dosing

San Francisco-based Vial has dosed the first asthma patient in a Phase Ib trial of its IL-13/TSLP bispecific antibody, which is engineered for potential...

15m ago
Equillium cleared to start Phase I trial of oral AhR modulator EQ504
Development

Equillium cleared to start Phase I trial of oral AhR modulator EQ504

La Jolla, California-based Equillium (Nasdaq: EQ) has received Australian regulatory and ethics clearance to begin a first-in-human Phase I trial of EQ504,...

26m ago
Genmab, AbbVie report 51% reduction in progression or death with frontline epcoritamab
Development

Genmab, AbbVie report 51% reduction in progression or death with frontline epcoritamab

Genmab (Nasdaq: GMAB) and AbbVie reported that adding epcoritamab to R-CHOP chemotherapy reduced the risk of disease progression or death by 51% in newly...

2h ago
TRexBio targets up to USD 133m in Nasdaq IPO
Business

TRexBio targets up to USD 133m in Nasdaq IPO

South San Francisco-based TRexBio has filed an amended S-1 to raise approximately USD 116.7 million to USD 133.3 million in a Nasdaq IPO, offering 8.33...

2h ago
Lilly expands Gate Bioscience partnership with potential USD 870m deal
Business

Lilly expands Gate Bioscience partnership with potential USD 870m deal

Gate Bioscience expanded its discovery partnership with Eli Lilly in a deal potentially worth more than USD 870 million. The agreement adds one target, with...

2h ago
Leiden Uni spinout RougeTx launches with USD 58m Series A for HHT program
Business

Leiden Uni spinout RougeTx launches with USD 58m Series A for HHT program

RougeTx, based in the Netherlands, has launched with a USD 58 million Series A to advance RTX-001, its lead programme for hereditary haemorrhagic...

3h ago
Italfarmaco and VeriSIM Life combine AI and HDAC expertise in USD 100m+ drug discovery deal
Business

Italfarmaco and VeriSIM Life combine AI and HDAC expertise in USD 100m+ drug discovery deal

Italy-based Italfarmaco S.p.A. and San Francisco-based VeriSIM Life, Inc. have entered a discovery collaboration to develop novel small-molecule inhibitors...

19h ago
Sernova and Seraxis close USD 11.2m financing to advance merger and T1D cell therapy trial
Business

Sernova and Seraxis close USD 11.2m financing to advance merger and T1D cell therapy trial

Sernova Biotherapeutics (TSX: SVA; OTC: SEOVF) and Seraxis Holdings, Inc. have closed a USD 11.2 million financing to support their proposed merger into...

19h ago
The AllSci BriefFree, systematic R&D and deal news. Daily.
WashU researchers show blocking T-cell brain entry protects against tau-driven damage in mice
Discovery

WashU researchers show blocking T-cell brain entry protects against tau-driven damage in mice

Researchers at Washington University School of Medicine in St. Louis found that blocking the chemokine receptor CXCR3 reduced T-cell infiltration into the...

22h ago
Nhwa licenses sleep-disorder drug to Somnivera for up to USD 517.5m outside Greater China
Business

Nhwa licenses sleep-disorder drug to Somnivera for up to USD 517.5m outside Greater China

Jiangsu Nhwa Pharmaceutical Co. (Shenzhen Stock Exchange: 002262) announced the grant of an exclusive license to Tennessee-based Somnivera, Inc. for...

22h ago
Ractigen’s RAG-18 triggers utrophin upregulation in first-in-human DMD data
Development

Ractigen’s RAG-18 triggers utrophin upregulation in first-in-human DMD data

Suzhou, China-based Ractigen Therapeutics presented first-in-human Phase I data for RAG-18, a small activating RNA therapeutic for Duchenne muscular...

23h ago
Rina-S delivers 46% response rate and 12-month durability in platinum-resistant ovarian cancer
Development

Rina-S delivers 46% response rate and 12-month durability in platinum-resistant ovarian cancer

Genmab (Nasdaq: GMAB) reported that rinatabart sesutecan (Rina-S), its folate receptor alpha (FRα)-targeted antibody-drug conjugate, achieved a confirmed...

23h ago
Jaypirca breaks into first-line CLL/SLL with FDA approval
Regulatory & Policy

Jaypirca breaks into first-line CLL/SLL with FDA approval

The US FDA approved Jaypirca (pirtobrutinib) as monotherapy for adults with previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma...

23h ago
Italfarmaco licenses JCR's brain-penetrating Hunter syndrome therapy for US, Europe and Latin America
Business

Italfarmaco licenses JCR's brain-penetrating Hunter syndrome therapy for US, Europe and Latin America

Italy-based Italfarmaco S.p.A. and Japan-based JCR Pharmaceuticals Co., Ltd. (Tokyo Stock Exchange: 4552) have agreed an exclusive license covering...

1d ago
BioMarin reports durable five-year outcomes with Pombiliti/Opfolda in late-onset Pompe disease
Development

BioMarin reports durable five-year outcomes with Pombiliti/Opfolda in late-onset Pompe disease

BioMarin Pharmaceutical (Nasdaq: BMRN) reported long-term efficacy and safety data from the PROPEL open-label extension study of cipaglucosidase alfa...

1d ago