AllSci News
Aspen’s sasineprocel shows motor improvements in Phase I/IIa Parkinson’s disease trial
Aspen Neuroscience, a San Diego–based clinical-stage regenerative medicine company, announced 12-month data from its Phase I/IIa ASPIRO clinical trial evaluating sasineprocel (ANPD001),…
FDA approves J&J’s Icotyde for plaque psoriasis in adults and adolescents
The US FDA has approved Icotyde (icotrokinra) for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients aged 12 years…
Dalriada, Topos Bio form small molecule discovery partnership for intrinsically disordered proteins
Toronto-based Dalriada Drug Discovery and San Francisco-based Topos Bio have entered a research collaboration to advance small-molecule drug discovery against intrinsically disordered…
HCW Biologics hands Phase I development of tri-specific fusion immunotherapeutic to China’s Trimmune
HCW Biologics Inc. (NASDAQ: HCWB), a Florida-based biopharma, has closed an exclusive worldwide license for HCW11-006, a preclinical fusion immunotherapeutic, signed with…
BioVie spinoff Option Therapeutics moving towards IPO for USD 21.8m
Option Therapeutics Inc. (NYSE American: OPTN), a clinical-stage biopharmaceutical company incorporated in Delaware, filed for an initial public offering of...
R1 Therapeutics licenses Alebund’s pan-phosphate transporter inhibitor alongside Series A launch
R1 Therapeutics, a newly formed clinical-stage company, has licensed exclusive rights to develop and commercialize Alebund Pharmaceuticals’ AP306 outside Greater China under…
NRx Pharma plans NDA for NRX-100 ketamine in severe depression after Type C meeting
NRx Pharmaceuticals (Nasdaq: NRXP) has confirmed its intention to submit a New Drug Application (NDA) to the US FDA for NRX-100 (preservative-free…
Immutep’s LAG3 drug eftilagimod alfa halted in Phase III for NSCLC due to futility
Sydney-based Immutep Limited announced that the Independent Data Monitoring Committee for its TACTI-004 Phase III trial recommended discontinuation of the study evaluating…
Sana reports 14-month survival of hypoimmune islet cells without immunosuppression in Type 1 diabetic patient
Seattle-based Sana Biotechnology announced 14-month follow-up data from a first-in-human study of UP421, an allogeneic islet cell therapy engineered with the company’s…
Ultragenyx gene therapy DTX301 cuts plasma ammonia in Phase III OTC deficiency trial
Novato, California-based Ultragenyx Pharmaceutical announced Phase III results for DTX301 (avalotcagene ontaparvovec), an AAV8 gene therapy for ornithine transcarbamylase deficiency, reporting a…
Regenxbio’s gene therapy RGX-202 posts positive early data in Duchenne muscular dystrophy
Regenxbio Inc., a Maryland-based gene therapy company, announced new interim data from the Phase I/II AFFINITY DUCHENNE trial of RGX-202 in patients…
Pilatus puts CD36-blocking “metabolic checkpoint” antibody into Phase I solid tumor study
Pilatus Biosciences has dosed the first patient in a Phase I clinical trial of PLT012, a humanized monoclonal antibody that blocks CD36-mediated…
Enodia swoops on troubled Kezar’s Sec61 pipeline
France-based Enodia Therapeutics and the San Francisco-based biotech Kezar Life Sciences, Inc. (NASDAQ: KZR) announced that Enodia has acquired Kezar’s preclinical assets…
Vertex hopeful on first-mover status for BAFF+APRIL povetacicept after Phase III data
Vertex Pharmaceuticals announced positive results from a pre-specified Week 36 interim analysis of the RAINIER Phase III trial evaluating povetacicept in adults…
Dianthus Therapeutics raises USD 400m via share offering
Dianthus Therapeutics, Inc. (Nasdaq: DNTH), a clinical-stage biotechnology company based in New York City and Waltham, Massachusetts, announced a proposed USD 400…
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