AllSci News

N-Zyme repurposing HIV drug fosamprenavir for laryngopharyngeal reflux disease
N-Zyme Biomedical, a clinical-stage company headquartered in Delaware, announced the initiation of a Phase II trial of fosamprenavir for laryngopharyngeal...
Artiva’s NK cell therapy takes FDA RMAT status for rheumatoid arthritis
San Diego-based Artiva Biotherapeutics, Inc. (Nasdaq: ARTV) announced receipt of US FDA Regenerative Medicine Advanced Therapy (RMAT) designation for AlloNK (AB-101) in…

TG Therapeutics aiming to expand Briumvi to myasthenia gravis after positive early data
TG Therapeutics (Nasdaq: TGTX) reported Phase I data showing that subcutaneous ublituximab (Briumvi), its glycoengineered anti-CD20 B-cell depleting...

Ethyreal launches with USD 101 million to develop dual Graves' disease and TED therapy
Cambridge, Massachusetts-based Ethyreal Bio has emerged from stealth with USD 101 million in financing to advance ETHY-001, a monoclonal antibody targeting...
Orionis and Novartis partner on molecular glue platform in potential USD 1.4b deal
Boston and Belgium-based Orionis Biosciences and Novartis have expanded a strategic research collaboration that began in 2020, signing a new multi-year agreement…

Laekna takes stake in 'new co.' Vasqu Bio, hands license to PI3Kα inhibitor in USD 527m deal
Laekna (HKEX: 02105) has licensed its pre-clinical PI3Kα inhibitor LAE118 to Vasque Bio in a deal worth up to USD 527 million, positioning a...

Denmark's HERVolution to apply immunotherapy to metabolic disease under license from University of Copenhagen
HERVolution Therapeutics, a Denmark-based biotech applying immunotherapy to metabolic disease, has secured an exclusive license from the University of...

SonoThera's ultrasound-guided gene med platform gets USD 125 in Series B backing
San Francisco-based SonoThera has closed an oversubscribed USD 125 million Series B financing round to advance its ultrasound-mediated nonviral genetic...
Dana-Farber Cancer Institute receives USD 50m Yawkey Foundation grant for Boston hospital
Dana-Farber Cancer Institute has received a USD 50 million philanthropic grant from the Yawkey Foundation to support construction of a planned 300-bed...

Ideaya raises USD 300m in concurrent offering for darovasertib and DLL3 ADC pipeline
South San Francisco-based IDEAYA Biosciences (Nasdaq: IDYA) announced the pricing of an underwritten public offering of common stock and pre-funded...

Eloxx Pharma raises USD 66m in public offering to advance nonsense mutation platform
Arlington, Massachusetts-based Eloxx Pharmaceuticals, Inc. (Nasdaq: ELOX) announced the pricing of a USD 66 million public offering of common stock and...

FDA accepts Takeda's Entyvio application for pediatric ulcerative colitis and Crohn's disease
Pediatric patients with inflammatory bowel disease represent one of the most therapeutically underserved populations in gastroenterology, and Takeda's...

Summit Therapeutics to raise USD 500m via public offering as ivonescimab trials progress
Miami-based Summit Therapeutics Inc. (Nasdaq: SMMT) announced a proposed underwritten public offering of common stock targeting USD 500 million in gross...

University of Minnesota wins NIH support for CAR Treg and lipid nanoparticle cGVHD therapies
The University of Minnesota has received a USD 1.58 million NIH R01 grant from the National Heart, Lung, and Blood Institute to investigate the cellular...

Novoron Bio's Alzheimer's tau screening platform supported by NIH monies
San Diego-based Novoron Bioscience, Inc. has received a USD 1.25 million NIH R44 SBIR grant from the National Institute on Aging to develop a human...
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