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Development

HAYA's HTX-001 targets cardiac fibrosis through WISPER lncRNA reprogramming in nHCM patients

HAYA Therapeutics has dosed the first cohort in the Phase I/IIa clinical trial of HTX-001, an antisense oligonucleotide targeting WISPER lncRNA in patients...

May 21
Business

PharmAla Biotech grants Jupiter Neuro US rights to ALA-002 MDMA therapeutic for USD 100m

PharmAla Biotech (CSE: MDMA; OTCQB: MDXXF, Toronto) has signed a term sheet to grant Jupiter Neurosciences (Nasdaq: JUNS, Jupiter, Florida) exclusive,...

May 20
Business

Eli Lilly adds non-viral genetic meds platform via USD 202m Engage Bio acquisition

Eli Lilly has acquired San Carlos, California-based Engage Biologics Inc. for up to USD 202 million in cash, adding the company's Tethosome non-viral DNA...

May 20
Development

Dyne Therapeutics initiates Phase III FORZETTO trial of z-rostudirsen in Duchenne muscular dystrophy

Dyne Therapeutics (Nasdaq: DYN) has announced the initiation of the Phase III FORZETTO trial of zeleciment rostudirsen (z-rostudirsen) in Duchenne muscular...

May 20
Development

Remepy's drug-software combo produces significant symptoms reduction in Phase IIa Parkinson's disease trial

Remepy reported Phase IIa clinical trial results for Hybridopa (levodopa/carbidopa plus DopApp), its drug-software combination for Parkinson's disease,...

May 20
Business

Forlong Bio secures USD 17.5m in Pre-B funding for cytokine pipeline advancement

Suzhou-based Forlong Biotechnology has closed a Series Pre-B financing round of approximately RMB 120 million (USD 17.5 million) to advance its IL-15 and...

May 20
News

Qiagen and Nvidia integrate knowledge graph infrastructure with BioNeMo platform for AI drug discovery

Qiagen (NYSE: QGEN; Frankfurt Prime Standard: QIA), headquartered in Venlo, Netherlands, and Nvidia have announced a collaboration integrating Nvidia’s accelerated computing infrastructure…

May 20
News

Exelixis and Merck expand zanzalintinib collaboration into resected colorectal cancer

Exelixis (Nasdaq: EXEL), based in Alameda, California, and Merck announced a clinical development collaboration to evaluate zanzalintinib in combination with Keytruda Qlex…

May 20
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Development

Pfizer's 25vPnC pneumococcal vaccine shows superior serotype 3 responses in Phase II pediatric study

Pfizer (NYSE: PFE) reported Phase II results for its 25-valent pneumococcal conjugate vaccine candidate PF-07872412 (25vPnC) in healthy infants, with...

May 20
News

BMS shakes with Anthropic to deploy Claude Enterprise across global pharma operations

Bristol Myers Squibb (BMS; NYSE: BMY, Princeton, NJ) and Anthropic announced a strategic agreement to deploy Claude AI as the company’s shared…

May 20
News

Bayer’s Hyrnuo gains FDA Priority Review for sBLA in first-line NSCLC

Bayer announced receipt of US FDA Priority Review for a supplemental New Drug Application (sNDA) for Hyrnuo (sevabertinib), an oral reversible HER2/EGFR…

May 20
Regulatory & Policy

IntraBio aiming Aqneursa as first ever treatment for ataxia-telangiectasia

IntraBio files for AQNEURSA approval in ataxia-telangiectasia, seeking first-ever treatment for the rare neurological disease

May 20
Discovery

Gladstone Institutes receives USD 2m NIAID award for AI-guided phage therapy development

Gladstone Institutes has received a USD 2 million NIAID P01 award to establish the PhAIge Therapy Center, a multi-project preclinical program applying...

May 20
Discovery

UCSD receives USD 2.5m NIDA grant for Brain-FRAMe HIV research program

University of California, San Diego has received a USD 2.5 million RM1 grant from the National Institute on Drug Abuse to launch Brain-FRAMe, a...

May 20
News

Roche and Medicines Patent Pool expand baloxavir marboxil access across 129 low- and middle-income countries

Roche (SIX: ROG) and the Medicines Patent Pool (MPP) announced the signing of a voluntary licence agreement covering baloxavir marboxil (Xofluza), Roche’s…

May 20