Discovery
Tumor-distal lymph nodes may preserve immune reservoir supporting checkpoint therapy in NSCLC
Researchers at China-based Tianjin Medical University have identified that mediastinal lymph nodes anatomically distant from the primary tumor — previously...
Intero Biosystems's intestinal organoid platform backed by SBIR
Aurora, Colorado-based Intero Biosystems Inc. has received a USD 1.05 million Small Business Innovation Research (SBIR) Phase II grant from the National...
Astrin Bio and University of Minnesota report plasma proteomics classifier for early-stage breast cancer detection
Researchers at Saint Paul, Minnesota-based Astrin Biosciences, working with collaborators at the University of Minnesota Masonic Cancer Center, Mayo Clinic,...
Kite-backed study identifies inherited genetic predictors of CAR-T toxicity and expansion
Researchers at Massachusetts General Hospital in Boston, working with colleagues at the Broad Institute of MIT and Harvard and Santa Monica,...
Scripps advances dual-target mammarenavirus antivirals with NIAID funding
Scripps Research Institute has received a USD 1.62 million NIAID R01 grant to advance preclinical development of two novel small-molecule inhibitors...
Promatix advances EGFR × EphA2 cis-bispecific ADC with Innovate UK funding
UK-based Promatix Biosciences has received a non-dilutive Innovate UK Biomedical Catalyst grant to advance PBS293-exatecan, its lead EGFR × EphA2...
Einstein College of Medicine receives USD 13.8m NIAID grant for rapid-response viral vaccine platform
Albert Einstein College of Medicine has received a USD 13.8 million NIAID U19 cooperative agreement to lead PROVIDENT, a 13-institution consortium...
Feinstein Institutes releases comprehensive vagus nerve atlas from 30 donors, advancing bioelectronic medicine device design
Researchers at the Feinstein Institutes for Medical Research, the research arm of Northwell Health in Manhasset, New York, have released the most detailed...
NIH backs MD Anderson with USD 3m grant to validate tumor prediction NAMs in CRC trials
The University of Texas MD Anderson Cancer Center has received a USD 3 million NIH cooperative agreement to validate predictive tumor models — combining in...
Isoprene advances AR-V7-targeting molecular glue degrader with NCI funding
Baltimore-based Isoprene Pharmaceuticals, Inc. has received a USD 1.02 million NCI SBIR R44 grant to complete IND-enabling preclinical studies for...
NIH backs Mount Sinai's FSH-blocking antibody for Down syndrome Alzheimer's
Icahn School of Medicine at Mount Sinai has received a USD 1,210,250 NIH R01 grant to test whether blocking follicle-stimulating hormone (FSH) can reduce...
Phoenix Nest gets NIH backing for Sanfilippo syndrome gene therapy manufacturing
Phoenix Nest, a Brooklyn, New York-based biotechnology company, has received a USD 1.49 million NIH SBIR grant to fund manufacturing and analytical...
Michigan secures NIH funding to advance ASO therapy for CLN3 Batten disease
The University of Michigan at Ann Arbor has received a USD 1.35 million NIH U01 grant to conduct IND-enabling studies for an antisense oligonucleotide (ASO)...
Cambium secures NCI funding to advance VIP checkpoint therapy for AML
Cambium Oncology LLC, an Atlanta-based biotech, has received a USD 1.05 million SBIR fast-track grant from the National Cancer Institute to advance...
NIH backs overdose-limiting oxycodone prodrug with USD 5.28m award
Ensysce Biosciences (La Jolla, California) has received a USD 5.28 million U01 cooperative agreement from the National Institute on Drug Abuse to continue...
The AllSci Brief
Free, systematic R&D and deal news. Daily.