Discovery

Sparian Biosciences advances non-opioid pain drug toward clinical testing with NIDA support
Sparian Biosciences, a New York-based for-profit company, has received a USD 3.1 million NIDA UG3 grant to advance SBS-147, an oral non-opioid analgesic,...

JCVI receives USD 1.79 million NIAID grant to advance phage therapy toward FDA IND
J. Craig Venter Institute has received a USD 1.79 million NIAID R01 award to advance a five-phage therapeutic cocktail targeting antibiotic-resistant...
Cūrza backed by NIAID award for novel ribosomal inhibitor to combat multidrug-resistant infections
Curza Inc, a Salt Lake City-based antibiotic developer, has received a USD 1 million NIAID SBIR award to advance CZ-02, a novel class of oral antibiotics...
Sanford Burnham Prebys develops single-construct gene therapy to boost cardiac cell reprogramming in heart failure
Sanford Burnham Prebys Medical Discovery Institute, the La Jolla, California-based nonprofit research institute, has received a USD 1.6 million NIH R01...

Talus Bio backed by NCATS for AI platform to unlock transcription factors as drug targets
Talus Bioscience Inc, a Seattle-based drug discovery company, has received a USD 1.03 million SBIR R44 grant from the National Center for Advancing...

Ohio State University develops exosome-based RNA nanotechnology to silence mutant KRAS in mCRC
Ohio State University has received a USD 1.43 million NCI R01 grant to develop an exosome-based RNA nanotechnology platform targeting mutant KRAS in...

Rejuvenation Technologies backed with grant to move TERT mRNA into clinic for alcoholic hepatitis
Rejuvenation Technologies, Inc., a Mountain View, California-based biotechnology company, has received a USD 2.06 million NIAAA SBIR Commercialization...

Chicago Uni engineers bacteria to deliver immunotherapy directly to pancreatic tumors
The University of Chicago has received a USD 1.75 million National Cancer Institute R01 award to develop genetically engineered Bifidobacterium as a...

Henry Ford Health secures NIH funding for inhaled IPF therapy based on vonoprazan
Henry Ford Health + Michigan State University Health Sciences has received a USD 1.56 million NIH R01 grant from the National Heart, Lung, and Blood...

VCU advances dual EGFR/HER2 degradation strategy to overcome drug resistance in lung cancer
Virginia Commonwealth University has received a USD 1.74 million National Cancer Institute R01 award to advance preclinical evaluation of PEPDG278D, a...

Broad Institute advances gene editing to permanently lower prion protein and halt neurodegeneration
The Broad Institute has received a USD 11.3 million NIH U19 renewal to advance gene editing approaches aimed at permanently lowering prion protein (PrP)...

Memorial Sloan Kettering builds diverse stem cell knockout catalog to study autism and type 2 diabetes genes
Memorial Sloan-Kettering Cancer Center has received a USD 1.78 million NIH UM1 renewal to continue building a large-scale catalog of human gene knockout...

UCSF engineers ALPPL2-targeted bispecific TCE aiming for solid cancers
University of California, San Francisco has received a USD 1.64 million National Cancer Institute R01 award to develop a bispecific T cell engager targeting...

Feinstein Institutes secures NIH funding for inflammation and Alzheimer's disease research
Feinstein Institutes for Medical Research has received USD 4.9 million in NIH grants across two multi-year awards targeting acute inflammation and...

Washington Uni secures USD 16.5m to expand DIAN-TU anti-tau Alzheimer's platform
The Washington University neurology department in St. Louis has received a USD 16.5 million NIA R01 renewal to continue the Dominantly Inherited Alzheimer...
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