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LTZ Therapeutics raises USD 38m for myeloid engager immunotherapy pipeline

LTZ Therapeutics, a clinical-stage immunotherapy company headquartered in Redwood City, California, has closed an oversubscribed USD 38 million financing...

May 7
Discovery

Mount Sinai, Memorial Sloan Kettering explore colorectal cancer immune resistance with quadruple checkpoint combo

Researchers at the Icahn School of Medicine at Mount Sinai in New York, with contributions from Memorial Sloan Kettering Cancer Center, report that a...

May 7
Business

CellCentric backed with USD 220m in Series D for myeloma hope inobrodib

Cambridge-based CellCentric has closed an oversubscribed USD 220 million Series D financing round to advance pivotal clinical development of inobrodib, its...

May 6
Business

BioOra gains global CAR T-cell therapy rights from Wellington Zhaotai for Atla-cel development

BioOra Limited has signed a binding Heads of Terms agreement with Wellington Zhaotai Therapies Limited granting BioOra exclusive rights to develop and...

May 6
Business

Avalo picks up USD 375m via share offering to support IL-1beta development

Wayne, Pennsylvania-based Avalo Therapeutics (Nasdaq: AVTX) announced the pricing of an underwritten public offering totaling USD 375 million in gross...

May 6
Development

Hoth Therapeutics' HT-001 shows efficacy for EGFR inhibitor-associated dermatologic toxicities in Phase IIa trial

Hoth Therapeutics reported interim Phase IIa results for HT-001 in cancer patients experiencing EGFR inhibitor-associated dermatologic toxicities, according...

May 6
Development

Kali Therapeutics' CD19 × CD3 bispecific T-cell engager KT502 ready for Phase I in rheumatoid arthritis

Kali Therapeutics has initiated a first-in-human Phase I trial of KT502, a CD19 × CD3 bispecific T-cell engager administered subcutaneously, in adults with...

May 6
Development

Fosun/Teva's anti-PD-1/IL-2 fusion protein FXB0871 to enter the clinic in China for PD-(L)1-resistant solid tumors

A first-in-human (FIH) clinical trial of FXB0871 (TEV-56278), an anti-PD-1/IL-2 antibody-cytokine fusion protein, has been registered in China, with HKEX-...

May 6
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Development

Cenna Biosciences' amyloid beta-targeting peptide 8M2D enters Phase I/b trial for early Alzheimer's disease

Cenna Biosciences is moving its synthetic peptide 8M2D — also referred to as Nubytide™ in prior company disclosures and as P8 in earlier academic literature...

May 6
News

Epicrispr and Forge Biologics partner on AAV manufacturing for EPI-321 FSHD gene therapy

Epicrispr Biotechnologies and Forge Biologics have announced an AAV manufacturing partnership to support the clinical development of EPI-321, an investigational gene therapy…

May 6
Business

Abivax raises USD 45m in share offering for royalty repurchase

France-based Abivax SA (Nasdaq/Euronext Paris: ABVX) announced the pricing of a USD 45 million (EUR 38.5 million) offering of American Depositary Shares to...

May 6
Business

Signadori Bio closes EUR 11.1m seed extension to advance monocyte engineering platform

Paris-based Signadori Bio SAS has closed a EUR 11.1 million seed extension round to advance its in vivo monocyte engineering platform for solid tumours,...

May 6
Business

Bayer to acquire Perfuse Therapeutics for USD 2.45b to expand ophthalmology pipeline with PER-001

Bayer has agreed to acquire South San Francisco-based Perfuse Therapeutics, Inc. for a total potential value of up to USD 2.45 billion, comprising a USD 300...

May 6
News

Clearmind seeks European patent for non-hallucinogenic neuroplastogen PTSD compounds

Clearmind Medicine Inc. (Vancouver, Canada), a clinical-stage biotech focused on neuroplastogen therapeutics, announced the filing of a European patent application covering novel…

May 6
News

ZYUS Life Sciences receives USPTO patent for cannabichromene pain management formulation

ZYUS Life Sciences Corporation (Canada), a clinical-stage company listed on the TSXV under the ticker ZYUS, received US Patent No. 12,616,704 from…

May 6