AllSci News

Systematic, data-driven science coverage · Thursday, September 10, 2026
The AllSci BriefFree, systematic R&D and deal news. Daily.
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NodThera rebrands as Rezera as ruvonoflast meets Phase II endpoint, eyes Phase III in PAD
Development

NodThera rebrands as Rezera as ruvonoflast meets Phase II endpoint, eyes Phase III in PAD

Ruvonoflast (NT-0796), an oral NLRP3 inflammasome inhibitor developed by Boston-based Rezera Inc. (formerly NodThera), met its primary endpoint in the...

2m ago
Mindera Health partners with UPenn to investigate quinacrine mechanism in lupus
Business

Mindera Health partners with UPenn to investigate quinacrine mechanism in lupus

Mindera Health is collaborating with University of Pennsylvania researchers to investigate why quinacrine helps some patients with cutaneous lupus—and...

22m ago
Seismic launches global Phase III trial of istaroxime in cardiogenic shock
Development

Seismic launches global Phase III trial of istaroxime in cardiogenic shock

Durham, North Carolina-based Seismic Pharmaceuticals has launched a global Phase III trial of istaroxime in cardiogenic shock, a life-threatening condition...

4h ago
UpDoc receives up to USD 9.2m from ARPA-H for autonomous heart failure AI system
Business

UpDoc receives up to USD 9.2m from ARPA-H for autonomous heart failure AI system

Palo Alto-based UpDoc has been selected as a lead performer in the Advanced Research Projects Agency for Health (ARPA-H) ADVOCATE program, receiving an...

5h ago
Cytonics crowdfunds USD 4.8m to advance A2M biologic into Phase Ib/IIa osteoarthritis study
Business

Cytonics crowdfunds USD 4.8m to advance A2M biologic into Phase Ib/IIa osteoarthritis study

Jupiter, Florida-based Cytonics Corporation has completed a USD 4.8 million gross-proceeds financing campaign, bringing total capital raised to USD 47...

5h ago
Insightec spinout Lotus Neuro launches brain drug delivery platform
Business

Insightec spinout Lotus Neuro launches brain drug delivery platform

Lotus Neuro, a clinical-stage biotechnology company spun out of focused ultrasound specialist Insightec, launched publicly with a platform designed to...

5h ago
Disc Medicine’s DISC-3405 reduces phlebotomy needs in Phase II polycythemia vera trial
Development

Disc Medicine’s DISC-3405 reduces phlebotomy needs in Phase II polycythemia vera trial

Massachusetts-based Disc Medicine (Nasdaq: IRON) released Phase II data showing that DISC-3405, an anti-TMPRSS6 monoclonal antibody, sharply reduced...

5h ago
Tempus wins USD 9.5m in ARPA-H funding to develop autonomous cardiology AI
Business

Tempus wins USD 9.5m in ARPA-H funding to develop autonomous cardiology AI

Tempus AI (Nasdaq: TEM) secured up to USD 9.5 million from the Advanced Research Projects Agency for Health (ARPA-H) to develop and clinically validate an...

5h ago
The AllSci BriefFree, systematic R&D and deal news. Daily.
Roche moves Enspryng toward first approved MOGAD therapy
Regulatory & Policy

Roche moves Enspryng toward first approved MOGAD therapy

Roche (SIX: RO; OTCQX: RHHBY) announced a US FDA Priority Review award for a supplemental Biologics License Application (sBLA) for Enspryng (satralizumab),...

6h ago
McGill and Mount Sinai researchers identify PRMT7 as suppressor of CD8+ T cell expansion
Discovery

McGill and Mount Sinai researchers identify PRMT7 as suppressor of CD8+ T cell expansion

A protein arginine methyltransferase acts as a previously unrecognized suppressor of cytotoxic T cell proliferation, offering a potential new target for...

7h ago
Lee's Pharm picks up 1cBio's preclinical PARP1 inhibitor for China and SE Asia
Business

Lee's Pharm picks up 1cBio's preclinical PARP1 inhibitor for China and SE Asia

Lee's Pharmaceutical Holdings (HKEX: 00950) has licensed exclusive rights to develop, manufacture, and commercialize OC-3, a preclinical selective PARP1...

22h ago
Independent research teams validate Apeximmune's PLA2G2D target for overcoming anti-PD-1 resistance
Development

Independent research teams validate Apeximmune's PLA2G2D target for overcoming anti-PD-1 resistance

A Nature publication has given South San Francisco-based Apeximmune Therapeutics substantial external validation, with two independent research teams...

22h ago
Stanford spinout TwoStep raises USD 62.5m as lead peptide-drug conjugate clears FDA IND
Business

Stanford spinout TwoStep raises USD 62.5m as lead peptide-drug conjugate clears FDA IND

San Carlos, California-based TwoStep Therapeutics has raised USD 62.5 million in an oversubscribed Series A financing round, coinciding with US FDA...

22h ago
Alebund gains FDA IND clearance for IgA-cleaving AP308 in IgA nephropathy
Regulatory & Policy

Alebund gains FDA IND clearance for IgA-cleaving AP308 in IgA nephropathy

Alebund Pharmaceuticals (HKEX: 09637) received US FDA clearance of its investigational new drug (IND) application for AP308, an engineered recombinant IgA...

22h ago
IDEAYA, Servier expand darovasertib into Phase III adjuvant uveal melanoma
Development

IDEAYA, Servier expand darovasertib into Phase III adjuvant uveal melanoma

San Francisco-based IDEAYA Biosciences (Nasdaq: IDYA) and France-based Servier announced that the first patient has been dosed in OptimUM-11, a global Phase...

23h ago